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Discover 2.0 Microwave Synthesis

Discover 2.0 Microwave Synthesis




The Discover® 2.0 is the premier microwave reactor for performing any organic or inorganic synthetic chemistry. Featuring a best-in-class 300 mL single-mode microwave cavity and intuitive software with a 10″ touchscreen interface, it is possible to program a reaction in seconds and achieve the best synthetic yield in minutes.



  • Widest pressurized vessel sizes for a single-mode microwave – 10mL, 35mL, 100mL
  • IR Temperature Sensor that sees through glass and Teflon® (iWave®)
  • Vent and reseal technology for safe handling of over-pressurization (ActiVent)
  • Variable speed magnetic stirring and rapid compressed air cooling
  • Upgrade options: Autosamplers – 12/48 positions; Gaseous Addition, Sub-ambient temperature, Flow cells

Microwave Advantage

The Absolute Best Approach for Chemical Synthesis

Microwave synthesis provides unique heating benefits for synthetic chemistry.1-3 Reactions are heated volumetrically, directly, and instantaneously, faster and more efficiently than any other form of heating. These microwave characteristics give organic chemists better product yield and more control over reaction conditions for precise results in materials and inorganic chemistry. Microwave energy is the industry standard for medicinal chemistry, nanomaterials synthesis, and academic teaching labs, owing to these clear advantages.

Microwave Synthesis – Heating vs. Conventional

Conventional Heating


Microwave Synthesis – Heating vs. Conventional

Microwave Heating

1Dudley, G. B.; Richert, R.; Stiegman, A. E. Chem. Sci. 2015, 6, 2144-2152.
2Chen, P.-K.; Rosana, M. R.; Dudley, G. B.; Stiegman, A. E. J. Org. Chem. 2014, 79, 7425-7436.
3Hunt, J.; Ferrari, A.; Lita, A.; Crosswhite, M.; Ashley, B.; Stiegman, A. E. J. Phys. Chem. C 2013, 51, 26871-26880

iWave Temperature Control for Microwave Synthesis



iWave – IR That Sees Through Glass and Teflon

For the first time, a single-mode microwave synthesizer reactor utilizing iWave, an intelligent IR sensor that can see through glass and Teflon and measures the temperature of your sample NOT the vessel! Based on new technology this powerful update eliminates the need for costly and fragile internal fiber-optic probes while providing the most accurate and responsive temperature measurement available.

Safely Vent Pressurized Microwave Synthesis Vials



Activent — Safe, Pressurized Reactions

The Discover 2.0 patented pressure management technology is the latest advance in automated pressure control and the safest way to perform pressurized reactions. This system automatically relieves gaseous byproducts as they form during the reaction, venting safely through exhaust tubing at the back of the system. This significantly reduces vial failures and allows your reactions to reach higher temperatures while requiring only an easy-to-use snap on cap without the need for crimping tools.

Microwave Synthesis Vessels



Use The Widest Range of Sealed Vessels Available

Discover 2.0 offers the widest range of high-temperature, high-pressure sealed reaction vessels, standard. Perform pressurized reactions in either 10, 35, or 100 mL vials. Alternatively, run non-pressurized, open vessel reactions in standard laboratory glassware up to a 125 mL round-bottom flask. If your chemistry etches glass (HF or strong inorganic bases), use a silicon carbide vessel or even disposable Teflon®liners to get the best results.

Camera for Microwave Synthesis


Integrated Camera

Observe Your Reaction

The 5 megapixel camera included standard with the Discover 2.0 can be used to record still images or video footage of reactions. Observation is a basic part of science, and this is the perfect tool for documentation and publication support.

View Technical Data


Intuitive Software For Any Chemist

Fully customizable methods and cycles for any synthetic chemistry. User level access with full password protection and complete audit trail traceability. Method import reduces programming errors and allows easy access to niche chemistries.

Microwave Synthesis Software

Create Microwave Methods Directly from Literature

Method programming takes only seconds with the integrated conventional-to-microwave converter. Any standard literature preparation can be automatically changed to a microwave reaction in only a few clicks.

Power Control for Microwave Heating

Complete Control of Your Reaction

The Discover 2.0 reactor features more flexibility in control type than any other microwave synthesizer. Heat to a target temperature quickly and consistently with standard control modes or explore the nature of microwave heating and control reaction pressures with advanced programs.



Remote programming and data viewing for a Microwave Synthesizer

Review Data Whenever, Wherever

Generate reports, review data, and export to a local network drive all from the Discover 2.0. No need for a USB to move information to and from the instrument.



Flexible Software for a Microwave Synthesizer

Your Chemistry on Your Instrument

Fully customize all aspects of the Discover 2.0. Power control, method parameters, data management, user logins, color themes, sounds, unit name and many more parameters are all at your fingertips.



Customize your Discover 2.0

Customize your system to fit your chemistry needs.

Autosampler for running batches on a Microwave Synthesizer


Set up multiple reactions to run overnight with the 12- or 48- place autosampler. Both autosamplers can accommodate the 10 and 35 mL sealed vessels.

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Gaseous Addition for Hydrogenations and Carbonylation Reactions with Microwave Synthesis

Gas Addition Kit

The Gas Addition accessory is the only system specially designed for a single-mode microwave reactor with gaseous reagents. Perform hydrogenations, carbonylations, or other reactions with gaseous reagents or simply use the vessel to ensure an inert atmosphere during microwave irradiation.

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Sub-ambient temperature reactions with microwave synthesis


The CoolMate™ is the only commercially available microwave accessory, designed to perform reactions at sub-ambient temperatures. Reactions such as lithiation, carbohydrate synthesis, and other temperature-sensitive chemistries can now benfit from the use of microwave energy. Accelerate reactions, even at temperatures as low as -80 °C.

View Literature Review – Mitsunobu Reaction
View Literature Review – Glycosylation


Use of Flow chemistry with microwave synthesis

Flow Cells

Increase your reaction throughput with the 10 and 80 mL continuous flow cells.

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